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Curasight

The history of Curasight

Curasight is founded in 2013 in Denmark based on a strong understanding of nuclear medicines and more than a decade of research at Copenhagen’s University hospital, Rigshospitalet and the University of Copenhagen, where the potential of targeting the urokinase-type plasminogen activator receptor (uPAR) in solid cancer tumors was identified.

Led by Professor Andreas Kjær (CSO & Co-founder), the research demonstrated how uPAR could be used not only to visualize aggressive cancer biology through PET imaging, but also as a highly selective target for radionuclide therapy. These insights formed the basis for Curasight’s theranostic approach and the establishment of the company.

Since its establishment, Curasight has focused on advancing a uPAR-based platform combining diagnostic uPAR-PET imaging (uTRACE®) and targeted radioligand therapy (uTREAT®) to identify, target, and eliminate all types of aggressive solid tumors with unmatched precision.

Following its 2020 listing on Spotlight Market (~DKK 97 million raised), Curasight partnered uTRACE® with Curium in 2023 for global development and commercialization within diagnosis of prostate cancer.

Through the years Curasight has conducted nine clinical trials (450 patients) with uTRACE® in eight solid cancer types, demonstrating favorable biodistribution (precision) and safety data across solid tumors.

Curasight initiated its first Phase I uTREAT® clinical trial in glioblastoma in 2025.

2013

Curasight established to translate uPAR-based academic research into a commercial theranostic platform, combining cancer diagnostics and targeted radioligand therapy.

2020 - 2021

Successful IPO at Spotlight Stock Market, raising approx. DKK 97 million to support clinical development and platform expansion.

2022

Continued advancement and maturation of Curasight’s uPAR theranostics platform, with further development of uTRACE® and uTREAT®. Nine clinical trials (450 patients) with uTRACE® in eight different types of solid tumors.

2023

Strategic partnership agreement signed with Curium for the development and commercialization of uTRACE® within diagnosis of prostate cancer. Curasight retained all rights to uTREAT®.

2023

Preclinical studies demonstrate differentiated and strong anti-tumor efficacy of uTREAT®, supporting continued clinical of uTREAT® as a first-in-class radioligand therapy for multiple solid tumors.

2024

First patient enrolled in Phase II clinical trial of uTRACE® in diagnosis of prostate cancer.

2025

Phase I clinical trial of uTREAT® initiated in glioblastoma.